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FITC anti-human CD89 Antibody
产品名称:
FITC anti-human CD89 Antibody
产品类别:
抗体
产品编号:
354113
产品应用:
354113
[价格]
规格 价格 库存
25tests ¥ 1344 1

产品详情

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
African Green, Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Ag8.653 myeloma cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Monteiro RC, et al. 1992. J. Immunol. 148:1764.
  2. Shen L. 1992. J. Leukoc. Biol. 51:373.
  3. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
  4. Rogers KA, et al. 2004. Immunology 113:178.
Product Citations
  1. Rodda LB, et al. 2020. Cell. 184(1):169-183.e17. PubMed
RRID
AB_2728340 (BioLegend Cat. No. 354113) AB_2728341 (BioLegend Cat. No. 354114)

Antigen Details

Structure
Member of the immunoglobulin gene family and is a transmembrane glycoprotein, 55-100 kD
Distribution

Granulocytes, neutrophils, eosinophils, monocytes, macrophages

Function
Interacts with IgA opsonized targets and induces immunological processes such as phagocytosis, ADCC, and release of inflammatory mediators
Ligand/Receptor
IgA (monomeric, dimeric, polymeric and secretory IgA)
Cell Type
Eosinophils, Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area
Immunology
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Patry C, et al. 1996. J. Immunol. 156:4442.
2. de Wit, et al. 1995. J. Immunol. 155:1203.
3. Honorio-Fran?a AC, et al. 2001. J. Leukoc. Biol. 69:289.

Gene ID
2204 View all products for this Gene ID
UniProt
View information about CD89 on UniProt.org

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