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首页 > 抗体蛋白 > 抗体
Purified anti-MERTK (Mer) Antibody
产品名称：
Purified anti-MERTK (Mer) Antibody
产品类别：
抗体
产品编号：
677202
产品应用：
677202
[价格]
规格 价格 库存
100µg ￥ 3732 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Extracellular domain of recombinant partial-length human MERTK.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Graham DK, et al. 2006. Clin. Cancer Res. 9:2662.
  2. Sather S, et al. 2007. Blood 109:1026.
RRID
AB_2565900 (BioLegend Cat. No. 677202)

Antigen Details

Structure
999 amino acids with a predicted molecular weight of approximately 110 kD with the characteristic of the common NCAM (neural adhesion molecule)-related extracellular domain. Observed molecular weight is 140-160 kD due to different glycosylation patterns.
Distribution

Transmembrane protein. Preferentially expressed by macrophages, dendritic cells, natural killer cells, osteoclasts, Sertoli cells, and retinal pigmental epithelium cells.

Function
Macrophage activation, apoptotic cell engulfment, platelet aggregation, and clot stability.
Interaction
TNK2, LGALS3, TUB, TULP1, GAS6, and VAV1.
Cell Type
Dendritic cells
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Signal Transduction
Antigen References

1. Pierce AM, et al. 2014. Brain Res. 1542:206.
2. Cummings CT, et al. 2013. Clin. Cancer Res. 19:5275.
3. Nguyen KQ, et al. 2013. Autoimmunity 46:294.
4. Qingxian L, et al. 2010. Front Biol. 5:227.
5. Linger RM, et al. 2008. Adv. Cancer Res. 100:35.
6. Lemke G, et al. 2008. Nat. Rev. Immunol. 8:327.
7. Graham DK, et al. 2006. Clin. Cancer Res. 9:2662.
8. Sather S, et al. 2007. Blood 109:1026.

Gene ID
10461 View all products for this Gene ID
UniProt
View information about MERTK on UniProt.org

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