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首页 > 抗体蛋白 > 抗体
APC anti-mouse CD135 Antibody
产品名称：
APC anti-mouse CD135 Antibody
产品类别：
抗体
产品编号：
135309
产品应用：
135309
[价格]
规格 价格 库存
25µg ￥ 1140 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse Flt3 transfected cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Sergejeva S, et al. 2004. Blood 103:1270.
  2. Auffray C, et al. 2009. J. Exp. Med. 206:595.
  3. Chiba H, et al. 2013. Am J Physiol Cell Physiol. 305:693. PubMed
Product Citations
  1. Lawson H, et al. 2021. Stem Cell Reports. 16:2784. PubMed
  2. Jabbar S, et al. 2022. Exp Hematol Oncol. 11:83. PubMed
  3. Mitroulis I et al. 2018. Cell. 172(1-2):147-161 . PubMed
  4. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  5. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  6. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  7. Kobayashi H, et al. 2020. STAR Protoc. 1:100078. PubMed
  8. Paiva RS, et al. 2021. Eur J Immunol. 51:1968. PubMed
  9. Schlager S, et al. 2015. J Leukoc Biol. 98: 837 - 850. PubMed
  10. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  11. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  12. Jia W, et al. 2021. Nat Commun. 12:2118. PubMed
  13. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  14. Gao S, et al. 2022. Cell Res. 32:38. PubMed
  15. Comazzetto S et al. 2018. Cell stem cell. 24(3):477-486 . PubMed
  16. Nagai M, et al. 2020. Cell. 178(5):1072-1087.e14.. PubMed
  17. Ding P, et al. 2022. Bone Res. 10:42. PubMed
  18. Jonas B, et al. 2016. PLoS One. 11: 0159189. PubMed
  19. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  20. Kobayashi H, et al. 2020. Cell Reports. 28(1):145-158.e9.. PubMed
  21. Di Genua C, et al. 2019. Haematologica. 104:2215. PubMed
  22. Oppezzo A, et al. 2020. J Clin Invest. 130:1377. PubMed
  23. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  24. Li Z, et al. 2017. Sci Rep. 7:40380. PubMed
  25. Jin J, et al. 2020. Cell Reports. 30(12):4124-4136. PubMed
  26. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  27. Giridhar P, et al. 2016. J Immunol. 197(11):4228-4239. PubMed
RRID
AB_1953264 (BioLegend Cat. No. 135309) AB_2107050 (BioLegend Cat. No. 135310)

Antigen Details

Structure
A 135-150 kD molecule belonging to the tyrosine kinase receptor family.
Distribution

Expressed on early B lymphoid lineage cells in juvenile and adult bone marrow, primitive myeloid progenitors within the BM CD34+ cell population.

Function
Regulate the growth of hematopoietic stem cells and promote the survival of primitive hematopoietic progenitor cells.
Ligand/Receptor
Flk-2/FLT3 ligand
Cell Type
B cells, Hematopoietic stem and progenitors
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Waskow C, et al.Nat. Immunol. 9:676
2. Veiby OP, et al. 1996. Blood 88(4):1256
3. Veiby OP, et al. 1996. J. Immunol. 157(7):2953
4. Mattews W, et al. 1991. Cell. 65(7):1143
5. Hannum C, et al. 1994. Nature 368(2):643
6. Ogawa M, et al. 1998. Exp Hematol. 26(6):478

Gene ID
14255 View all products for this Gene ID
UniProt
View information about CD135 on UniProt.org

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