PE/Cyanine7 anti-human CD41/CD61 Antibody
- 产品名称：
- PE/Cyanine7 anti-human CD41/CD61 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 359811
- 产品应用：
- 359811
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2052 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human platelets
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for relevant formats) include: immunoprecipitation1 and blocking (aggregation)2. The Ultra-LEAF? purified antibody (Endotoxin <0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 359804).
A2A9/6 is recognized as having high affinity to gpIIb/IIIa. It has been shown to inhibit platelet aggregation induced by a variety of agonists and the initiation of clot formation.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Basani RB, et al. 1996. Blood. 88:167. (IP)
- Bennett JS, et al. 1983. Proc. Natl. Acad. Sci. USA. 80:2417. (Block)
- RRID
- AB_2564346 (BioLegend Cat. No. 359811) AB_2564347 (BioLegend Cat. No. 359812)
- Structure
- Complex of CD41 and CD61 through non-covalent association.
- Distribution
- Platelets and megakaryocytes.
- Function
- Mediates attachment to cells of diverse matrix proteins.
- Ligand/Receptor
- Fibrinogen, RGD-containing adhesive proteins such as vonWillebrand Factor (vWF) and fibronectin.
- Cell Type
- Platelets, Megakaryocytes
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Matsumura-Takeda K, et al. 2007. Stem Cell. 25:862.
2. Corbel C, et al.?2005. 49:279.
3. Bennett JS, et al. 1983. Proc. Natl. Acad. Sci. USA. 80:2417.?
4. Clemetson KJ, et al.?1994. Curr. Opin. Hematol. 1:388.
- Gene ID
- 3690 View all products for this Gene ID 3674 View all products for this Gene ID
- UniProt
- View information about CD41/CD61 on UniProt.org
