Purified anti-C/EBP β (2 isoforms C/EBP &beta
- 产品名称：
- Purified anti-C/EBP β (2 isoforms C/EBP &beta
- 产品类别：
- 抗体
- 产品编号：
- 626001
- 产品应用：
- 626001
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length mouse C/EBP β protein
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
A16 monoclonal antibody recognizes C/EBP?-FL (31kD) and C/EBP?-LAP (29kD) isoforms, but not C/EBP?-LIP (16kD).
- Application References
(PubMed link indicates BioLegend citation) -
- Lee YM, et al.1996. Mol. Cell. Biol. 16:4257
- Su, et al. 2003. J. Biol. Chem. 278:51150.
- Product Citations
-
- Brina D, et al. 2015. Nat Commun. 6: 8261. PubMed
- RRID
- AB_2097742 (BioLegend Cat. No. 626001) AB_2097741 (BioLegend Cat. No. 626002)
- Structure
- C/EBP transcription factor family, basic leucine zipper, dimer. Mouse C/EBP has three isoforms that include C/EBPβ-FL, C/EBPβ-LAP, and C/EBPβ-LIP (31kD, 29kD and 16kD, respectively).
- Distribution
-
Nuclear
- Function
- Transcription factor in immune, inflammatory, acute-phase, cytokine, collagen type I genes
- Interaction
- CEBP-α, CEBP-β, CEBP-δ, CEBP-γ, CEBP-ε, CEBP-ζ
- Modification
- Phosphorylation, Ubiquitination
- Biology Area
- Cell Biology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Chang C, et al. 1990. Mol. Cell Biol. 10:6642.
2. Eaton E, et al. 2001. J. Cell Physiol. 189:91.
3. Piwien-Pilipuk G, et al. 2002. J. Biol. Chem. 277:44557.
4. Hattori T, et al. 2003. Oncogene. 22:1273.
- Regulation
- Growth hormone
- Gene ID
- 12608 View all products for this Gene ID
- UniProt
- View information about C/EBP beta on UniProt.org
