Purified anti-Mesothelin Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3312	1

规格

价格

库存

100µg

￥ 3312

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human recombinant mesothelin
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB -?Quality tested
IHC-P - Verified
Recommended Usage: Optimal concentration of usage is 0.1 - 0.5 ?g/mL for WB. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 10.0 ?g/mL is suggested. The optimal concentration should be determined by titration for each individual assay of interest.
Application Notes: Precursor: 70 kDa. Mature form (N-glycosylated): 46-48kDa.

Clone A15125D does not cross react with mouse (in-house tested).?
RRID: AB_2687055 (BioLegend Cat. No. 696302)

Structure: The human MSLN gene encodes a ~71 kD precursor protein of 622 amino acids. The MSLN precursor is cleaved into two products, a ~31 kD mature megakaryocyte potentiating factor and a ~40 kD GPI-anchored membrane-bound mature mesothelin
Distribution: Mesothelial cells lining the pleura, peritoneum, and pericardium and tumor cells
Function: Cell adhesion; may promote cancer cell survival, proliferation, and metastasis; confers resistance to cytotoxic drug-induced apoptosis
Interaction: Cancer cells
Ligand/Receptor: CA125/MUC16
Biology Area: Cancer Biomarkers, Cell Adhesion, Cell Biology
Molecular Family: Cytokines/Chemokines
Antigen References: 1.?Kojima T,?et al.?1995.?J. Biol. Chem.?270:21984.
2.?Chang K and Pastan I. 1996.?Proc. Natl. Acad. Sci. USA?93:136.
3.?Rump A,?et al.?2004.?J. Biol. Chem.?279:9190.
4.?Bharadwaj U,?et al.?2011.?Mol. Cancer?10:106.
5.?Chen SH,?et al.?2013.?Sci. Rep.?3:1870.
6.?Tang Z,?et al.?2013.?Anticancer Agents Med. Chem.?13:276.
Gene ID: 10232 View all products for this Gene ID
UniProt: View information about Mesothelin on UniProt.org