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Purified anti-α-Synuclein, 80-96 Antibody
产品名称:
Purified anti-α-Synuclein, 80-96 Antibody
产品类别:
抗体
产品编号:
848301
产品应用:
848301
[价格]
规格 价格 库存
25µg ¥ 1068 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
KLH-Conjugated synthetic peptide that included amino acid residues 80-96 of human α-synuclein.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P -?Quality tested
Direct ELISA, WB -?Verified

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.0 - 10 ?g/ml is suggested. For Direct ELISA, the suggested use of this reagent is 0.02 - 3.0 per ml. For Western blotting, the suggested use of this reagent is 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This clone does not cross-react with ? or ?-synucleins using ELISA and WB as detection method.

Product Citations
  1. Gustavsson N, et al. 2021. Acta Neuropathol Commun. 9:153. PubMed
RRID
AB_2650687 (BioLegend Cat. No. 848301) AB_2650688 (BioLegend Cat. No. 848302)

Antigen Details

Structure
α-synuclein's canonical isoform is a 140 amino acid protein with an apparent molecular mass of 14 kD.
Distribution

Tissue distribution: Primarily nervous system, but lower expression in other tissues such as blood and skin.
Cellular distribution: Cytoskeleton, cytosol, ?lysosome, mitochondria, nucleus, plasma membrane, and extracellular.

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
α-Synuclein, Phospho-Proteins
Antigen References

1. Mor DE,?et al. 2016.?Neurobiol Dis. 88:66.?PubMed
2. Jucker M & Walker LC. 2013.?Nature. 501(7465):45.?PubMed
3. Bartels T,?et al.?2011.?Nature. 477(7362): 107.?PubMed?
4. Devine MJ,?et al.?2011.?Mov Disord.?26:2160.?PubMed

Gene ID
6622 View all products for this Gene ID
UniProt
View information about alpha-Synuclein, 80-96 on UniProt.org

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