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Biotin anti-α-Synuclein, 80-96 Antibody
产品名称:
Biotin anti-α-Synuclein, 80-96 Antibody
产品类别:
抗体
产品编号:
848305
产品应用:
848305
[价格]
规格 价格 库存
25µg ¥ 1344 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
KLH-Conjugated synthetic peptide that included amino acid residues 80-96 of human α-synuclein.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

WB - Quality tested
IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.2 - 1.0 ?g/mL.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.5 - 10 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This clone does not cross-react with ? or ?-synucleins using ELISA and WB as detection method.

RRID
AB_2832860 (BioLegend Cat. No. 848305) AB_2832861 (BioLegend Cat. No. 848306)

Antigen Details

Structure
α-synuclein's canonical isoform is a 140 amino acid protein with an apparent molecular mass of 14 kD.
Distribution

Tissue distribution: Primarily nervous system, but lower expression in other tissues such as blood and skin.
Cellular distribution: Cytoskeleton, cytosol, ?lysosome, mitochondria, nucleus, plasma membrane, and extracellular.

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
α-Synuclein, Phospho-Proteins
Antigen References

1. Mor DE,?et al. 2016.?Neurobiol Dis. 88:66.?PubMed
2. Jucker M & Walker LC. 2013.?Nature. 501(7465):45.?PubMed
3. Bartels T,?et al.?2011.?Nature. 477(7362): 107.?PubMed?
4. Devine MJ,?et al.?2011.?Mov Disord.?26:2160.?PubMed

Gene ID
6622 View all products for this Gene ID
UniProt
View information about alpha-Synuclein, 80-96 on UniProt.org

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