Purified anti-human Tim-4 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 2748	1

规格

价格

库存

100µg

￥ 2748

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human TIM-4- IgV Fc, fusion protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 9F4 recognizes the FG loop of human Tim-4¹.

Application References (PubMed link indicates BioLegend citation)

Kobayashi N, et al. 2007. Immunity 27:927.

Product Citations

De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed

RRID

AB_11126746 (BioLegend Cat. No. 354002)

Antigen Details

Structure: Type 1 transmembrane glycoprotein and mucin domain containing protein 4.
Distribution: Splenic CD14+, macrophages, immature DC.
Function: Tim-1 ligation to Tim-4 induces T cell proliferation, promotes cytokine production, and aids in the regulation of Th2 immunity.
Ligand/Receptor: Phosphatiylserine is the receptor of Tim-4, and Tim-4 is a ligand of Tim-1.
Cell Type: Dendritic cells, Macrophages
Biology Area: Immunology
Antigen References: 1.?Kobayashi N, et al. 2007. Immunity 27:927.
2. Meyers JH, et al. 2005. Nat. Immunol. 6:455.
3. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454.
4. Shakhov AN, et al. 2004. Eur. J. Immunol. 34:494.
Gene ID: 91937 View all products for this Gene ID
UniProt: View information about Tim-4 on UniProt.org

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