PE/Cyanine7 anti-human Tim-4 Antibody
- 产品名称：
- PE/Cyanine7 anti-human Tim-4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 354005
- 产品应用：
- 354005
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2112 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TIM-4- IgV Fc, fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone 9F4 recognizes the FG loop of human Tim-41.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Kobayashi N, et al. 2007. Immunity 27:927.
- RRID
- AB_2564541 (BioLegend Cat. No. 354005) AB_2564542 (BioLegend Cat. No. 354006)
- Structure
- Type 1 transmembrane glycoprotein and mucin domain containing protein 4.
- Distribution
-
Splenic CD14+, macrophages, immature DC.
- Function
- Tim-1 ligation to Tim-4 induces T cell proliferation, promotes cytokine production, and aids in the regulation of Th2 immunity.
- Ligand/Receptor
- Phosphatiylserine is the receptor of Tim-4, and Tim-4 is a ligand of Tim-1.
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Immunology
- Antigen References
-
1.?Kobayashi N, et al. 2007. Immunity 27:927.
2. Meyers JH, et al. 2005. Nat. Immunol. 6:455.
3. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454.
4. Shakhov AN, et al. 2004. Eur. J. Immunol. 34:494.
- Gene ID
- 91937 View all products for this Gene ID
- UniProt
- View information about Tim-4 on UniProt.org
