Purified anti-CRMP2 Antibody
- 产品名称：
- Purified anti-CRMP2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 869001
- 产品应用：
- 869001
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 ?g per ml.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.5 - 1.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2814627 (BioLegend Cat. No. 869001) AB_2814628 (BioLegend Cat. No. 869002)
- Structure
- CRMP2 is a 572 amino acid protein with predicted and observed molecular mass of ~ 63 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Cytosol, plasma membrane, and cytoskeleton
- Function
- CRMP2 forms homotetramers or heterotetramers with other CRMP proteins, and regulates axonal growth and guidance, neuronal growth cone collapse, and migration.
- Interaction
- CRMP2 forms homotetramers and heterotetramers with CRMP1, DPYSL3, DPYSL4 or DPYSL5. It interacts with HTR4, CLN6, and, MICALL1.
- Cell Type
- Astrocytes, Neurons, Oligodendrocytes
- Biology Area
- Cell Motility/Cytoskeleton/Structure, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Cytoskeletal Proteins, Microfilaments, Microtubules, Scaffold Proteins
- Antigen References
-
- Hensley K, et al. 2016. J Alzheimers dis. 53(1):1
- Quach TT, et al. 2015. Mol Psychiatry. 20(9):1037
- Ip JP, et la. 2014. Neuroscientist. 20(6):589 ?
- Gene ID
- 1808 View all products for this Gene ID 12934 View all products for this Gene ID 25416 View all products for this Gene ID
- UniProt
- View information about CRMP2 on UniProt.org
