Purified anti-human CD335 (NKp46) Antibody
- 产品名称：
- Purified anti-human CD335 (NKp46) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 331902
- 产品应用：
- 331902
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NKp46-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone 9E2 has been shown to block NK activation through NKp46.6
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
- Kalberer CP, et al. 2003. Blood 102:127.
- Chen Y, et al. 2007. J. Immunol. 179:2766.
- Jarahian M, et al. 2009. J. Virol. 83:8108. PubMed
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Achdout H. et al. 2010. J. Virol. 84:3993.
- Product Citations
-
- Gadalla R, et al. 2022. STAR Protoc. 3:101643. PubMed
- Nguyen R, et al. 2021. Cancer Immunol Immunother. 70:721. PubMed
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Gao H, et al. 2021. J Virol. :. PubMed
- Rother S, et al. 2015. PLoS One. 10: 0135682. PubMed
- Fasbender F, et al. 2017. Front Immunol. 0.88125. PubMed
- Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
- Sanz–Ortega L, et al. 2019. Front Immunol. 1.85625. PubMed
- van Montfoort N, et al. 2018. Cell. 175:1744. PubMed
- Damele L, et al. 2021. Cancers (Basel). 13:. PubMed
- Li J, et al. 2021. Haematologica. 106:3115. PubMed
- Capuano C, et al. 2020. Cancer Immunol Immunother. 69:501. PubMed
- Jarahian M, et al. 2009. J Virol. 83:8108. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_1027637 (BioLegend Cat. No. 331902)
- Structure
- Type I membrane glycoprotein (46 kD)
- Distribution
-
Expressed on resting and activated NK cells
- Cell Type
- NK cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Mandelboim O and Porgador A. 2001. Int. J. Biochem. Cell Biol. 33:1147.
2. Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
3. Sivori S. 1999. Eur. J. Immunol. 29:1656.
- Gene ID
- 9437 View all products for this Gene ID
- UniProt
- View information about CD335 on UniProt.org
