PE/Fire™ 810 anti-human CD335 (NKp46) Antibo
- 产品名称：
- PE/Fire™ 810 anti-human CD335 (NKp46) Antibo
- 产品类别：
- 抗体
- 产品编号：
- 331953
- 产品应用：
- 331953
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 3036 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NKp46-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Fire? 810 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Fire? 810 has a maximum excitation of 488/561 nm and a maximum emission of 810 nm.
Excessive exposure to light, and commonly used fixation, permeabilization buffers can affect PE/Fire? 810 fluorescence signal intensity and spread. Please keep conjugates protected from light exposure. For more information and representative data, visit our Fire Dyes page. - Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone 9E2 has been shown to block NK activation through NKp46.6
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
- Kalberer CP, et al. 2003. Blood 102:127.
- Chen Y, et al. 2007. J. Immunol. 179:2766.
- Jarahian M, et al. 2009. J. Virol. 83:8108. PubMed
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Achdout H. et al. 2010. J. Virol. 84:3993.
- Structure
- Type I membrane glycoprotein (46 kD)
- Distribution
-
Expressed on resting and activated NK cells
- Cell Type
- NK cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Mandelboim O and Porgador A. 2001. Int. J. Biochem. Cell Biol. 33:1147.
2. Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
3. Sivori S. 1999. Eur. J. Immunol. 29:1656.
- Gene ID
- 9437 View all products for this Gene ID
- UniProt
- View information about CD335 on UniProt.org
