APC anti-human CD335 (NKp46) Antibody
- 产品名称：
- APC anti-human CD335 (NKp46) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 331917
- 产品应用：
- 331917
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1704 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NKp46-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone 9E2 has been shown to block NK activation through NKp46.6
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
- Kalberer CP, et al. 2003. Blood 102:127.
- Chen Y, et al. 2007. J. Immunol. 179:2766.
- Jarahian M, et al. 2009. J. Virol. 83:8108. PubMed
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Achdout H. et al. 2010. J. Virol. 84:3993.
- Product Citations
-
- Schmitz T, et al. 2021. J Reprod Immunol. 148:103424. PubMed
- Beatson RE, et al. 2021. Cell Rep Med. 2:100473. PubMed
- Memmer S, et al. 2016. J Biol Chem. 291(49):25427-25438. PubMed
- Shemesh A, et al. 2022. J Exp Med. 219:. PubMed
- Taouk G, et al. 2019. Sci Rep. 9:8756. PubMed
- RRID
- AB_2561649 (BioLegend Cat. No. 331917) AB_2561650 (BioLegend Cat. No. 331918)
- Structure
- Type I membrane glycoprotein (46 kD)
- Distribution
-
Expressed on resting and activated NK cells
- Cell Type
- NK cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Mandelboim O and Porgador A. 2001. Int. J. Biochem. Cell Biol. 33:1147.
2. Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
3. Sivori S. 1999. Eur. J. Immunol. 29:1656.
- Gene ID
- 9437 View all products for this Gene ID
- UniProt
- View information about CD335 on UniProt.org
