Alexa Fluor® 647 anti-human CD335 (NKp46) Anti
- 产品名称：
- Alexa Fluor® 647 anti-human CD335 (NKp46) Anti
- 产品类别：
- 抗体
- 产品编号：
- 331909
- 产品应用：
- 331909
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1692 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NKp46-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone 9E2 has been shown to block NK activation through NKp46.6
- Application References
(PubMed link indicates BioLegend citation) -
- Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
- Kalberer CP, et al. 2003. Blood 102:127.
- Chen Y, et al. 2007. J. Immunol. 179:2766.
- Jarahian M, et al. 2009. J. Virol. 83:8108. PubMed
- Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
- Achdout H. et al. 2010. J. Virol. 84:3993.
- Product Citations
-
- Pérez-Quintero L, et al. 2014. J Exp Med. 211:727. PubMed
- Huang RS, et al. 2021. Curr Protoc. 1:e246. PubMed
- El Costa H, et al. 2021. PLoS Pathog. 17:e1009367. PubMed
- Correia DV, et al. 2011. Blood. 118:992. PubMed
- Pahl JHW, et al. 2018. Cancer Immunol Res. 0.609027778. PubMed
- RRID
- AB_1027674 (BioLegend Cat. No. 331909) AB_2266918 (BioLegend Cat. No. 331910)
- Structure
- Type I membrane glycoprotein (46 kD)
- Distribution
-
Expressed on resting and activated NK cells
- Cell Type
- NK cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Mandelboim O and Porgador A. 2001. Int. J. Biochem. Cell Biol. 33:1147.
2. Nakajima H, et al. 2000. Eur. J. Immunol. 30:3309.
3. Sivori S. 1999. Eur. J. Immunol. 29:1656.
- Gene ID
- 9437 View all products for this Gene ID
- UniProt
- View information about CD335 on UniProt.org
