Purified anti-human VEGFR-3 (FLT-4) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1488	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

VEGFR extracellular domain protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IHC-P, IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for relevant formats) include: immunohistochemistry staining of frozen or paraffin embedded sections^1-3.

Application References (PubMed link indicates BioLegend citation)

Jussila L, et al. 1998. Cancer Res. 58:1599. (IHC)
Kilic N, et al. 2007. Blood 110:4223. (IHC)
Folpe A, et al. 2000. Mod. Pathol. 13:180. (IHC)

Product Citations

Karlas A, et al. 2016. Nat Commun. 7:11320. PubMed
Cooley L, et al. 2016. Sci Rep. 6: 25840. PubMed

RRID

AB_2561770 (BioLegend Cat. No. 356201) AB_2561771 (BioLegend Cat. No. 356202)

Antigen Details

Structure: Seven Ig-like domains in the extracellular domain, a single transmembrane helix, and a cytoplasmic region with tyrosine kinase activity
Distribution: Widely expressed in early embryogenesis endothelial cells, restrictly expressed on lymphatic endothelial cells in adults
Function: Mediates lymphangiogenesis in response to VEGF-C and VEGF-D, involved in cardiovascular development during embryogenesis
Ligand/Receptor: VEGF-C, VEGF-D
Biology Area: Cell Biology, Immunology, Signal Transduction
Molecular Family: Cytokine/Chemokine Receptors
Antigen References: 1. Tammela T, et al. 2008. Nature 454:656.
2. Partanen TA, et al. 2000. FASEB J. 14:2087.
3. Valtola R, et al. 1999. Am. J. Pathol. 154:1381.
4. Jussila L, et al. 1998. Cancer Res. 58:1599.
5. Galland F, et al. 1992. Genomics 13:475.
Gene ID: 2324 View all products for this Gene ID
UniProt: View information about VEGFR-3 on UniProt.org

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