APC anti-human VEGFR-3 (FLT-4) Antibody
- 产品名称：
- APC anti-human VEGFR-3 (FLT-4) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 356205
- 产品应用：
- 356205
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1932 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- VEGFR extracellular domain protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for relevant formats) include: immunohistochemistry staining of frozen or paraffin embedded sections1-3.
- Application References
(PubMed link indicates BioLegend citation) -
- Jussila L, et al. 1998. Cancer Res. 58:1599. (IHC)
- Kilic N, et al. 2007. Blood 110:4223. (IHC)
- Folpe A, et al. 2000. Mod. Pathol. 13:180. (IHC)
- RRID
- AB_2562276 (BioLegend Cat. No. 356205) AB_2562277 (BioLegend Cat. No. 356206)
- Structure
- Seven Ig-like domains in the extracellular domain, a single transmembrane helix, and a cytoplasmic region with tyrosine kinase activity
- Distribution
-
Widely expressed in early embryogenesis endothelial cells, restrictly expressed on lymphatic endothelial cells in adults
- Function
- Mediates lymphangiogenesis in response to VEGF-C and VEGF-D, involved in cardiovascular development during embryogenesis
- Ligand/Receptor
- VEGF-C, VEGF-D
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Tammela T, et al. 2008. Nature 454:656.
2. Partanen TA, et al. 2000. FASEB J. 14:2087.
3. Valtola R, et al. 1999. Am. J. Pathol. 154:1381.
4. Jussila L, et al. 1998. Cancer Res. 58:1599.
5. Galland F, et al. 1992. Genomics 13:475.
- Gene ID
- 2324 View all products for this Gene ID
- UniProt
- View information about VEGFR-3 on UniProt.org
