Alexa Fluor® 488 anti-mouse IL-17F Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 2112	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Mouse IL-17F-OVA

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser

Blue Laser (488 nm)

Application References (PubMed link indicates BioLegend citation)

Obregon-Henao A, et al. 2013. PLoS One. 8:80669. PubMed

Product Citations

Obregón-Henao A, et al. 2013. PLoS One. 8:80669. PubMed
Emg?rd J, et al. 2018. Immunity. 143:419. PubMed
Ma S, et al. 2022. Cell Rep. 38:110520. PubMed
Chong WP, et al. 2020. Immunity. 53(2):384-397.e5.. PubMed

RRID

AB_10660963 (BioLegend Cat. No. 517005) AB_10661903 (BioLegend Cat. No. 517006)

Antigen Details

Structure: Forms a 37 kD homodimer or heterodimer with IL-17A of the IL-17 family member.
Distribution: Th17 cells, mast cells, basophils, and epithelial cells.
Function: An important regulator of inflammatory responses, involved in cancer immunity and autoimmune responses as well.
Ligand/Receptor: IL-17R (CD217)
Cell Type: Th17, Mast cells, Basophils, Epithelial cells
Biology Area: Immunology, Innate Immunity
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Dong C. 2008. Immunol. Rev. 226:80.
2. Kolls JK, et al. 2004. Immunity 21:467.
3. Aggarwal S, et al. 2002. J. Leukoc. Biol. 71:1.
4. Yang XO, et al. 2008. J. Exp. Med. 205:1063.
5. Ishigame H, et al. 2009. Immunity 30:108.
6. Hu Y, et al. 2010. J. Immunol. 184:4307.
Gene ID: 257630 View all products for this Gene ID
UniProt: View information about IL-17F on UniProt.org

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