PE anti-human CD326 (EpCAM) Antibody
- 产品名称：
- PE anti-human CD326 (EpCAM) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 324205
- 产品应用：
- 324205
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1404 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- DU.4475 breast carcinoma
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the revelant formats) include: immunofluorescence,?immunohistochemistry3, and spatial biology (IBEX)4,5.
- Application References
(PubMed link indicates BioLegend citation) -
- Lammers R, et al. 2002. Exp. Hematol. 30:537.
- Schultz LD, et al. 2010. P. Natl. Acad. Sci. USA 107:13022. PubMed
- Human Protein Atlas http://www.proteinatlas.org/ENSG00000119888/antibody (IHC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Kawai T, et al. 2015. Clin Cancer Res. 21: 3081 - 3091. PubMed
- Stanzione M, et al. 2022. Sci Adv. 8:eabn1229. PubMed
- Civelekoglu O, et al. 2019. Lab Chip. 19:2444. PubMed
- Anderson DJ, et al. 2018. Nat Commun. 9:1373. PubMed
- Frank AC, et al. 2021. Theranostics. 11:7570. PubMed
- Vijayaraj P, et al. 2019. Cell Rep. 29:3488. PubMed
- Man L, et al. 2020. Cell Reports. 32(6):108027. PubMed
- Kathiriya JJ, et al. 2022. Nat Cell Biol. 24:10. PubMed
- Gómez-Zafra MJ, et al. 2020. Infect Immun. 88:00:00. PubMed
- Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
- Kinchen J et al. 2018. Cell. 175(2):372-386 . PubMed
- Hermann BP, et al. 2018. Cell Rep. 25:1650. PubMed
- Busslinger GA, et al. 2021. Cell Reports. 34(10):108819. PubMed
- Wang Z, et al. 2022. Front Oncol. 12:994087. PubMed
- Raposo B, et al. 2018. Nat Commun. 9:353. PubMed
- Frank AC, et al. 2019. Nat Commun. 10:1135. PubMed
- Shi G, et al. 2022. Methods Mol Biol. 2394:591. PubMed
- Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
- Ding S, et al. 2016. PLoS Pathog. 12:e1005929. PubMed
- Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
- Rodrigues Toste de Carvalho AL, et al. 2021. Nat Protoc. 16:1802. PubMed
- RRID
- AB_756079 (BioLegend Cat. No. 324205) AB_756080 (BioLegend Cat. No. 324206)
- Structure
- Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD.
- Distribution
-
Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis.
- Function
- Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation.
- Modification
- Glycosylated.
- Cell Type
- Embryonic Stem Cells, Epithelial cells
- Biology Area
- Cell Biology, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748.
3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.
- Gene ID
- 4072 View all products for this Gene ID
- UniProt
- View information about CD326 on UniProt.org
