FITC anti-human CD326 (EpCAM) Antibody
- 产品名称：
- FITC anti-human CD326 (EpCAM) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 324203
- 产品应用：
- 324203
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1272 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- DU.4475 breast carcinoma
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the revelant formats) include: immunofluorescence,?immunohistochemistry3, and spatial biology (IBEX)4,5.
- Application References
(PubMed link indicates BioLegend citation) -
- Lammers R, et al. 2002. Exp. Hematol. 30:537.
- Schultz LD, et al. 2010. P. Natl. Acad. Sci. USA 107:13022. PubMed
- Human Protein Atlas http://www.proteinatlas.org/ENSG00000119888/antibody (IHC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Zhao Q, et al. 2018. Cancer Res. 78:2370. PubMed
- Mair B et al. 2019. Nat Biomed Eng. 3(10):796-805 . PubMed
- Dong L, et al. 2020. BJU Int. 126:191. PubMed
- Cassandras M, et al. 2020. Nat Cell Biol. 1295:22. PubMed
- Peng J, et al. 2015. Cancer Res . 75: 5034 - 5045. PubMed
- Fasanya HO, et al. 2021. J Bone Oncol. 28:100357. PubMed
- Wimberger T, et al. 2020. Bioelectrochemistry. 134:107495. PubMed
- Barnicle A, et al. 2016. Physiol Genomics. 48: 257-273. PubMed
- Garcia TM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:943. PubMed
- Zheng X, et al. 2020. Cancer Res. 4414:80. PubMed
- Martins Garcia T, et al. 2022. Antibiotics (Basel). 11:. PubMed
- Urbaniak A, et al. 2020. J Biochem Mol Toxicol. 34:e22487. PubMed
- Choi J, et al. 2021. Nat Cell Biol. 23:953. PubMed
- Jung Y, et al. 2020. Prostate. 80:1145. PubMed
- Leonard NA, et al. 2021. Cancers (Basel). 13:. PubMed
- Liang D, et al. 2022. Front Cell Dev Biol. 10:883314. PubMed
- Dinh PC, et al. 2020. Nat Commun. 1.197222222. PubMed
- Kang H, et al. 2017. PLoS One. 12(6):e0180251. PubMed
- Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
- Tanimizu N, et al. 2013. J Cell Sci. 126:5239. PubMed
- McGinnis CS, et al. 2019. Nat Methods. 1.096527778. PubMed
- Jaganathan H, et al. 2014. PLoS One. 9:91986. PubMed
- Roos FJM, et al. 2021. Clin Transl Med. 11:e566. PubMed
- Liu J, et al. 2020. Cell Mol Gastroenterol Hepatol. . PubMed
- Xuan Z, et al. 2020. Am J Cancer Res. 0.458333333. PubMed
- Hansen FJ, et al. 2022. Int J Mol Sci. 23:. PubMed
- Wu SZ, et al. 2020. EMBO J. 39:e104063. PubMed
- Roca H, et al. 2013. PLoS One. 8:76773. PubMed
- Hao M, et al. 2021. Developmental Cell. 56(3):341-355.e5. PubMed
- RRID
- AB_756077 (BioLegend Cat. No. 324203) AB_756078 (BioLegend Cat. No. 324204)
- Structure
- Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD.
- Distribution
-
Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis.
- Function
- Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation.
- Modification
- Glycosylated.
- Cell Type
- Embryonic Stem Cells, Epithelial cells
- Biology Area
- Cell Biology, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748.
3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.
- Gene ID
- 4072 View all products for this Gene ID
- UniProt
- View information about CD326 on UniProt.org
