APC anti-mouse IL-17RB Antibody
- 产品名称：
- APC anti-mouse IL-17RB Antibody
- 产品类别：
- 抗体
- 产品编号：
- 146307
- 产品应用：
- 146307
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse IL-17RB - Fc chimera (human IgG1)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Schneider C, et al. 2018. Cell. 174:271. PubMed
- Luo W, et al. 2019. Mol Med Rep. 20:1007. PubMed
- Bi CS, et al. 2020. Cell Prolif. 53:e12827. PubMed
- RRID
- AB_2564513 (BioLegend Cat. No. 146307) AB_2564514 (BioLegend Cat. No. 146308)
- Structure
- Single pass type I transmembrane protein, 55.9 kD
- Distribution
- iNKT cells, innate lymphoid cells, Th2 cells
- Function
- Binds IL-25 with higher affinity than IL-17B, can block IL-25 mediated pathology
- Interaction
- TRAF6 and Act1
- Ligand/Receptor
- IL-25/IL-17E
- Cell Type
- NKT cells, Th2
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Hwang SY, et al. 2004. Arthritis Res. Ther. 6:R120.
2. Rickel EA,?et al. 2008. J. Immunol. 181:4299.
3. Terashima A, et al. 2008. J. Exp. Med. 205:2727.
- Gene ID
- 50905 View all products for this Gene ID
- UniProt
- View information about IL-17RB on UniProt.org
