Purified anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品名称：
- Purified anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353802
- 产品应用：
- 353802
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
- Jordan S, et al. 2020. Cell. 178(5):1102-1114.e17.. PubMed
- Cytlak U, et al. 2020. Immunity. 53(2):353-370. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_10983070 (BioLegend Cat. No. 353802)
- Structure
- Type II transmembrane glycoprotein; consists of a 35 amino acid (aa) cytoplasmic domain with an ITAM like motif, a 21 aa transmembrane segment, a 185 aa extracellular domain (ECD) that contains a stalk region, and one C-type lectin domain (CTLD).
- Distribution
-
Dendritic subsets including plasmacytoid dendritic cells.
- Function
- Cross-present antigen to CTL, phagocytosis necrotic cells.
- Interaction
- Necrotic cells.
- Ligand/Receptor
- Ubiquitous preformed acid-labile protein associated ligand(s).
- Cell Type
- Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens
- Antigen References
-
1. Poulin LF, et al. 2010. J. Exp. Med. 207:1261.
2. Sancho D, et al. 2009. Nature 458:899.
3. Huysamen C, et al. 2008. J. Biol. Chem. 283:16693.
- Gene ID
- 283420 View all products for this Gene ID
- UniProt
- View information about CD370 on UniProt.org
