PE anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品名称：
- PE anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353803
- 产品应用：
- 353803
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
- Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
- Findlay EG, et al. 2019. Oncoimmunology. 8:1608106. PubMed
- Schr?der M, et al. 2016. PLoS One. 11: 0157387. PubMed
- Molina MS, et al. 2021. Front Immunol. 12:699128. PubMed
- Lee J, et al. 2015. J Exp Med. 212:385. PubMed
- Wimmers F, et al. 2021. Cell. 184:3915. PubMed
- Breton G, et al. 2015. J Exp Med. 212:401. PubMed
- Cytlak U, et al. 2020. Immunity. 53(2):353-370. PubMed
- RRID
- AB_10959651 (BioLegend Cat. No. 353803) AB_10965546 (BioLegend Cat. No. 353804)
- Structure
- Type II transmembrane glycoprotein; consists of a 35 amino acid (aa) cytoplasmic domain with an ITAM like motif, a 21 aa transmembrane segment, a 185 aa extracellular domain (ECD) that contains a stalk region, and one C-type lectin domain (CTLD).
- Distribution
-
Dendritic subsets including plasmacytoid dendritic cells.
- Function
- Cross-present antigen to CTL, phagocytosis necrotic cells.
- Interaction
- Necrotic cells.
- Ligand/Receptor
- Ubiquitous preformed acid-labile protein associated ligand(s).
- Cell Type
- Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens
- Antigen References
-
1. Poulin LF, et al. 2010. J. Exp. Med. 207:1261.
2. Sancho D, et al. 2009. Nature 458:899.
3. Huysamen C, et al. 2008. J. Biol. Chem. 283:16693.
- Gene ID
- 283420 View all products for this Gene ID
- UniProt
- View information about CD370 on UniProt.org
