APC anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品名称：
- APC anti-human CD370 (CLEC9A/DNGR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 353805
- 产品应用：
- 353805
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1992 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Iwabuchi R, et al. 2021. Frontiers in Immunology. 12:643040. PubMed
- Forbester JL, et al. 2020. J Virol. 94:. PubMed
- Swartz AM, et al. 2022. Curr Protoc. 2:e410. PubMed
- Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
- Alhaj Hussen K, et al. 2017. Immunity. 47:680. PubMed
- Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
- Lavaert M, et al. 2020. Frontiers in Immunology. 1.610416667. PubMed
- RRID
- AB_2565518 (BioLegend Cat. No. 353805) AB_2565519 (BioLegend Cat. No. 353806)
- Structure
- Type II transmembrane glycoprotein; consists of a 35 amino acid (aa) cytoplasmic domain with an ITAM like motif, a 21 aa transmembrane segment, a 185 aa extracellular domain (ECD) that contains a stalk region, and one C-type lectin domain (CTLD).
- Distribution
-
Dendritic subsets including plasmacytoid dendritic cells.
- Function
- Cross-present antigen to CTL, phagocytosis necrotic cells.
- Interaction
- Necrotic cells.
- Ligand/Receptor
- Ubiquitous preformed acid-labile protein associated ligand(s).
- Cell Type
- Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens
- Antigen References
-
1. Poulin LF, et al. 2010. J. Exp. Med. 207:1261.
2. Sancho D, et al. 2009. Nature 458:899.
3. Huysamen C, et al. 2008. J. Biol. Chem. 283:16693.
- Gene ID
- 283420 View all products for this Gene ID
- UniProt
- View information about CD370 on UniProt.org
