FITC anti-human CD181 (CXCR1) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1272	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human CXCR1 transfected L1.2 cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)

Application Notes

Additional reported applications (for the relevant formats) include: The 8F1/CXCR1 antibody is useful for immunofluorescent staining and flow cytometric analysis of CXCR1 expression.

Product Citations

Risnik D, et al. 2017. Sci Rep. 7:15714. PubMed
Whilding LM, et al. 2019. Cancers (Basel). 11:5. PubMed
Kassianos A, et al. 2013. Am J Physiol Renal Physiol. 305:1391. PubMed

RRID

AB_439812 (BioLegend Cat. No. 320605) AB_439813 (BioLegend Cat. No. 320606)

Antigen Details

Structure: Seven transmembrane spanning, G protein-coupled receptor (CPCR), 67-70 kD, homodier or teterodimer with CXCR2
Distribution: Granulocytes, NK cells, subset of T cells, monocytes, endothelial cells, oligodendrocytes
Function: neutrophil activation, chemotaxis, angiogenesis
Ligand/Receptor: IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), GRO-a(CXCL1)
Cell Type: Endothelial cells, Granulocytes, Monocytes, Neutrophils, NK cells, Oligodendrocytes, T cells
Biology Area: Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Chuntharapai A, et al. 1994. J. Immunol. 153:5682.
2. Wilson S, et al. 2005. J. Biol. Chem. 280:28663.
3. Emadi S, et al. 2005. Blood 105:464.
4. Omari KM, et al. 2005. Brain 128:1003.
5. Juremalm M, G. Nilsson. 2005. Chem. Immunol. Allergy. 87:130.
6. Wolf M, et al. 1998. Eur. J. Immunol. 28:164
Gene ID: 3577 View all products for this Gene ID
UniProt: View information about CD181 on UniProt.org

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