Biotin anti-CX3CR1 Antibody
- 产品名称：
- Biotin anti-CX3CR1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 824004
- 产品应用：
- 824004
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a peptide sequence conjugated to KLH corresponding to amino acids 207-222 of the human CX3CR1 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration of 20 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in Immunoblotting (WB) and immunohistochemistry (IHC) for the relevant formats of this clone.
- RRID
- AB_2650684 (BioLegend Cat. No. 824004)
- Structure
- CX3CR1 is a 355 amino acid G-protein coupled receptor, 7 transmembrane regions protein with a molecular mass of 40 kD.
- Distribution
-
Tissue Distribution: central nervous system, and blood.
Cellular Distribution: plasma membrane.
- Function
- CX3CR1 is involved in cell recruitment during inflammation, and participates in cell adhesion and extravasation from blood vessels. It is also known as a coreceptor for HIV1.
- Ligand/Receptor
- CX3CL1 (fractalkine, neurotactin).
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Chen P, et al. 2016. BioMed. Res. Int. 2016. 8090918. PubMed
2. Sheridan GK, Murphy KJ. 2013. Open Biol. 3 (12) 130181. PubMed
- Gene ID
- 1524 View all products for this Gene ID
- UniProt
- View information about CX3CR1 on UniProt.org
