Pacific Blue™ anti-mouse CD309 (VEGFR2, Flk-
- 产品名称:
- Pacific Blue™ anti-mouse CD309 (VEGFR2, Flk-
- 产品类别:
- 抗体
- 产品编号:
- 121914
- 产品应用:
- 121914
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Rat-1 cells transfected with full-length mouse Flk
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with Pacific Blue? under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l. It is recommended that the reagent be titrated for optimal performance for each application.
* Pacific Blue? has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue? conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Violet Laser (405 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Kaburn N, et al. 1997. Development 124:2039.
- Product Citations
-
- Tarnawski L, et al. 2015. PLoS One. 10: 0135880. PubMed
- RRID
- AB_2283048 (BioLegend Cat. No. 121914)
- Structure
- Member of the tyrosine protein kinase family, sub-family CSF-1/PDGF. Single pass transmembrane receptor containing a protein kinase domain and seven immunoglobulin-like domains.
- Distribution
-
Expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels.
- Function
- Receptor for VEGF or VEGFC. Ligand binding plays a key role in vascular development and vascular permeability.
- Ligand/Receptor
- VEGF, VEGFC
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Patterson C, et al. 1995. J. Biol. Chem. 270:23111.
2. Quinn TP, et al. 1993. Proc. Natl. Acad. Sci. USA 90:7533.
- Gene ID
- 16542 View all products for this Gene ID
- UniProt
- View information about CD309 on UniProt.org