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Purified anti-Cytochrome c Antibody
产品名称:
Purified anti-Cytochrome c Antibody
产品类别:
抗体
产品编号:
612503
产品应用:
612503
[价格]
规格 价格 库存
50µl(5Westernblots) ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Most Species
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Horse cyt c-OVA
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
Upon receipt, store undiluted between 2°C and 8°C.
Application

WB -?Quality tested
ICC -?Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 ?l antibody per 5 ml antibody dilution buffer for each mini-gel. For immunocytochemistry, a concentration range of 1.0 - 3.0 ?g/ml (1:150-1:500 dilution) is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Jemmerson R, et al. 1991. Eur. J. Immunol. 21:143. (WB)
  2. Semenkova L, et al. 2003. Eur. J. Biochem. 270:4388. (WB)
Product Citations
  1. Kakimoto PA, et al. 2019. PLoS One. 14:e0211733. PubMed
  2. Chiang JC, et al. 2022. Antioxidants (Basel). 11:. PubMed
  3. Wu CH, et al. 2019. J Extracell Vesicles. 8:1588538. PubMed
  4. Kocabey S, et al. 2021. Nanomaterials (Basel). 11:. PubMed
  5. Asano M, et al. 2017. Sci Rep. 10.1038/s41598-017-11784-y. PubMed
  6. Duncan H 2010. Infect Immun. 78:3616. PubMed
  7. Bjedov I, et al. 2020. PLoS Genet. 16:e1009083. PubMed
  8. Liu X et al. 2018. Cell. 174(1):187-201 . PubMed
  9. Luis-Garcia ER, et al. 2021. Int J Mol Sci. 22:. PubMed
RRID
AB_2090157 (BioLegend Cat. No. 612503) AB_2292697 (BioLegend Cat. No. 612504)

Antigen Details

Structure
Heme binding domain; 15 kD
Distribution

Mitochondrial intermembrane space

Function
Component of electron transport chain; heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9
Interaction
Cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, Casp9
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Mitochondrial Function, Neuroscience, Neuroscience Cell Markers
Molecular Family
Mitochondrial Markers
Antigen References

1. Liu X, et al. 1996. Cell 86:147.
2. Li P, et al. 1997. Cell 91:479.
3. Zhang Z, et al. 2003. Gene 312:61.
4. Ferguson H, et al. 2003. J. Biol. Chem. 278:45793.

Gene ID
54205 View all products for this Gene ID
UniProt
View information about Cytochrome c on UniProt.org

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