Ultra-LEAF™ Purified anti-mouse CD268 (BAFF-
- 产品名称：
- Ultra-LEAF™ Purified anti-mouse CD268 (BAFF-
- 产品类别：
- 抗体
- 产品编号：
- 134107
- 产品应用：
- 134107
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse BAFF receptor transfected rat RBL cells
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
Block - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. The antibody blocks the binding between recombinant mouse BAFF (Cat. No. 591202) and recombinant mouse BAFFR (Cat. No. 756506). The ND50 range is 0.15 - 1.5 μg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Ng LG, et al. 2006. Eur. J. Immunol. 36:1837.
- Ng LG, et al. 2004. J Immunol. 173:807.
- Batten M, et al. 2000. J. Exp. Med. 192:1453.
- Fu L, et al. 2009. Blood 113:4627.
- RRID
- AB_2814029 (BioLegend Cat. No. 134107) AB_2876470 (BioLegend Cat. No. 134108)
- Structure
- A type III transmembrane TNF receptor family member
- Distribution
-
Expressed on most B cells, a small subset of CD4+ T cells.
- Function
- Play an importance role in B cell development, maturation, and survival.
- Ligand/Receptor
- BAFF (BLyS)
- Cell Type
- B cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Thompson JS, et al. 2001. Science 293:2108.
2. Schiemann B, et al. 2001. Science 293:2111.
3. Batten M, et al. 2000. J. Exp. Med. 192:1453.
4. Fu L, et al. 2009. Blood 113:4627.
- Gene ID
- 72049 View all products for this Gene ID
- UniProt
- View information about CD268 on UniProt.org
