Purified anti-mouse CD370 (CLEC9A, DNGR1) Antibody
- 产品名称：
- Purified anti-mouse CD370 (CLEC9A, DNGR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 143502
- 产品应用：
- 143502
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
ELISA, ICC, IP, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis.
- Application Notes
Additional reported applications (for the relevant formats) include: ELISA2, immunofluorescence microcopy1, immunoprecipitation1, and Western blotting1.
- Application References
(PubMed link indicates BioLegend citation) -
- Sancho D, et al. 2008. J. Clin. Invest. 118:2098. (IF, IP, WB)
- Joffre OP, et al. 2010. Eur. J. Immunol. 40:1255. (ELISA)
- Product Citations
-
- Luetke-Eversloh M, et al. 2014. PLoS Pathog. 10:1004441. PubMed
- RRID
- AB_11125169 (BioLegend Cat. No. 143502)
- Structure
- Type II transmembrane glycoprotein, consists of a 35 amino acid (aa) cytoplasmic domain with an ITAM-like motif, a 21 aa transmembrane segment, and a 185 extracellular domain (ECD) that contains a stalk region and one C-type lectin domain (CTLD)
- Distribution
-
Strictly expressed on CD8α+ dendritic cells, migratory CD103+ dendritic cells, and plasmacytoid dendritic cells
- Function
- Cross present antigen to CTL
- Interaction
- Necrotic cells
- Ligand/Receptor
- Ubiquitous preformed acid-labile protein associated ligand(s)
- Cell Type
- Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens
- Antigen References
-
Poulin LF, et al. 2012. Blood 119:6052.
- Gene ID
- 232414 View all products for this Gene ID
- UniProt
- View information about CD370 on UniProt.org
