PE anti-mouse CD21/CD35 (CR2/CR1) Antibody
- 产品名称：
- PE anti-mouse CD21/CD35 (CR2/CR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 123409
- 产品应用：
- 123409
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CD35/CFA
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Boackle S, et al. 2001 Immunity 15:775.
- de Andres B, et al. 2012. J. Immunol. 189:2300. PubMed
- Chiu YK, et al. 2014. J Immunol. 193:2207. PubMed
- Koening PA, et al. 2014. J Biol Chem. 289:34490. PubMed
- Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
- Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
- Product Citations
-
- Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
- Degn SE et al. 2017. Cell. 170(5):913-926 . PubMed
- Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
- Prokopec K, et al. 2016. J Immunol. 197: 2063 - 2068. PubMed
- Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
- Folgosa L, et al. 2013. J Immunol. 191:5951. PubMed
- Aschman T, et al. 2021. Int J Mol Sci. 22:. PubMed
- Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
- Souza SP, et al. 2021. PLoS Pathog. 17:e1010081. PubMed
- Liu R, et al. 2021. Mol Cell Biol. 41:e0025121. PubMed
- Liu R, et al. 2018. Front Immunol. 9:592. PubMed
- Firl DJ et al. 2018. eLife. 7 pii: e33051. PubMed
- Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
- Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
- Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
- Habener A, et al. 2021. J Allergy Clin Immunol. 147:2281. PubMed
- RRID
- AB_940411 (BioLegend Cat. No. 123409) AB_940413 (BioLegend Cat. No. 123410)
- Structure
- 145 kD/190 kD type I transmembrane glycoprotein
- Distribution
-
B cells, follicular dendritic cells
- Function
- Signal transduction
- Ligand/Receptor
- Associated with CD19/CD81. CD21 binds C3d, iC3b, and EBV; CD35 binds C3b, iC3b, C4b, and iC4b.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Kozono Y, et al. 1998. J. Immunol. 160:1562.
2. Shimizu I, et al. 2007. Blood 109:1773.
3. Roozendaal R and MC. Carroll. 2007. Immunol. Rev. 219:157.
- Gene ID
- 12902 View all products for this Gene ID 12946 View all products for this Gene ID
- UniProt
- View information about CD21/35 on UniProt.org
