FITC anti-mouse CD21/CD35 (CR2/CR1) Antibody
- 产品名称：
- FITC anti-mouse CD21/CD35 (CR2/CR1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 123407
- 产品应用：
- 123407
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CD35/CFA
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Boackle S, et al. 2001 Immunity 15:775.
- de Andres B, et al. 2012. J. Immunol. 189:2300. PubMed
- Chiu YK, et al. 2014. J Immunol. 193:2207. PubMed
- Koening PA, et al. 2014. J Biol Chem. 289:34490. PubMed
- Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
- Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
- Product Citations
-
- Morse M, et al. 2016. Lupus. 25: 81 - 87. PubMed
- Xu J, et al. 2021. Nature. 595:278. PubMed
- Chappaz S, et al. 2021. Cell Reports. 36(3):109430. PubMed
- Yang Y, et al. 2021. Nat Commun. 12:525. PubMed
- Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
- Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
- Li H, et al. 2020. Nature. 584:274. PubMed
- Hamilton J, et al. 2015. J Immunol. 194:5022. PubMed
- Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
- Ballesteros I, et al. 2020. Cell. 183(5):1282-1297.e18. PubMed
- Souza SP, et al. 2021. PLoS Pathog. 17:e1010081. PubMed
- Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
- Chen RJ, et al. 2022. iScience. 25:105595. PubMed
- Xu M, et al. 2013. J Immunol. 190:5436. PubMed
- Lu X, et al. 2019. Cell Rep. 28:472. PubMed
- Hamilton J,et al. 2017. J Immunol. 10.4049/jimmunol.1700888. PubMed
- Yoshida H, et al. 2019. Cell. 176:897. PubMed
- Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
- Chauvet S, et al. 2016. J Am Soc Nephrol. 27: 1665 - 1677. PubMed
- RRID
- AB_940403 (BioLegend Cat. No. 123407) AB_940405 (BioLegend Cat. No. 123408)
- Structure
- 145 kD/190 kD type I transmembrane glycoprotein
- Distribution
-
B cells, follicular dendritic cells
- Function
- Signal transduction
- Ligand/Receptor
- Associated with CD19/CD81. CD21 binds C3d, iC3b, and EBV; CD35 binds C3b, iC3b, C4b, and iC4b.
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Kozono Y, et al. 1998. J. Immunol. 160:1562.
2. Shimizu I, et al. 2007. Blood 109:1773.
3. Roozendaal R and MC. Carroll. 2007. Immunol. Rev. 219:157.
- Gene ID
- 12902 View all products for this Gene ID 12946 View all products for this Gene ID
- UniProt
- View information about CD21/35 on UniProt.org
