PerCP/Cyanine5.5 anti-human CD169 (Sialoadhesin, S
- 产品名称：
- PerCP/Cyanine5.5 anti-human CD169 (Sialoadhesin, S
- 产品类别：
- 抗体
- 产品编号：
- 346019
- 产品应用：
- 346019
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2112 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human Rhinovirus (HRV14) infected, monocyte derived-DCs
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting and inhibition of erythrocyte-rosetting with cells expressing CD169.
- Application References
(PubMed link indicates BioLegend citation) -
- Kirchberger S, et al. 2005. J. Immunol. 175:1145.
- Schrauf C, et al. 2009. J. Immunol. 183:4440.
- Product Citations
-
- Xiang Q, et al. 2021. Front Immunol. 12:661052. PubMed
- RRID
- AB_2860903 (BioLegend Cat. No. 346019) AB_2860904 (BioLegend Cat. No. 346020)
- Structure
- Type I single membrane-spanning lectin, 1709 amino acids, 210 kD, belongs to the immunoglobulin superfamily
- Distribution
-
Macrophages, dendritic cells
- Function
- Adhesion molecule
- Interaction
- α-2,3-linked sialic acid
- Ligand/Receptor
- CD227, CD43 and CD206
- Bioactivity
- Mediates sialic-acid dependent binding to granulocytes, monocytes, NK, B and T cells.
- Cell Type
- B cells, Dendritic cells, Macrophages
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules, Siglec Molecules
- Antigen References
-
1. Xiong YS, et al. 2009. Clin. Biochem. 42:1057.
2. Varki A, et al. 2009. Glycoconj J. 26:231.
3. Rempel H, et al. 2008. PLoS One. 3:e1967.
4. Crocker PR, et al. 2001. Trends Immunol. 22:337.
5. Hartnell A, et al. 2001. Blood 97:288.
- Gene ID
- 6614 View all products for this Gene ID
- UniProt
- View information about CD169 on UniProt.org
