PerCP/Cyanine5.5 anti-human CD123 Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-human CD123 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 306015
- 产品应用：
- 306015
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2112 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human IL-3Rα transfected COS cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Application Notes
Clone 6H6 does not inhibit IL-3 binding to low- or high-affinity IL-3Rs. Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, and immunohistochemical staining of acetone-fixed frozen sections2?and also paraformaldehyde fixed paraffin embedded tissue7.
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Sun Q, et al. 1996. Blood 87:83. (IP, WB)
- Herling M, et al. 2003. Blood 101:5007. (IHC)
- Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
- Martin-Gayo E, et al. 2010. Blood 115:5366. PubMed
- Chen SC, et al. 2010. Arch Dermatol Res. 302:113. PubMed
- Liu Y, et al. 2012. Food Chem Toxicol. 50:1920. PubMed
- Peduzzi E, et al. 2007. J. Invest. Dermatol. 127:638. (IHC)
- Product Citations
-
- Rosa TLSA, et al. 2022. Front Med (Lausanne). 9:899998. PubMed
- Gupta R, et al. 2022. Front Immunol. 13:886442. PubMed
- Mashiko S, et al. 2015. J Allergy Clin Immunol. 136: 351-359. PubMed
- Laing AG, et al. 2020. Nat Med. 26:1623. PubMed
- Woolsey C et al. 2019. Cell Rep. 28(12):3032-3046 . PubMed
- Jankeel A, et al. 2020. J Virol. :94. PubMed
- Bourdely P, et al. 2020. Immunity. 53(2):335-352. PubMed
- Gu C, et al. 2021. Front Immunol. 12:678036. PubMed
- Sureshchandra S, et al. 2021. iScience. 24:102690. PubMed
- Sureshchandra S, et al. 2022. Cell Rep. 39:110938. PubMed
- Manuel S, et al. 2013. AIDS Res Hum Retroviruses. 29:1273. PubMed
- Morell M, et al. 2022. EBioMedicine. 76:103808. PubMed
- Li M, et al. 2020. Nat Commun. 4051:11. PubMed
- RRID
- AB_2124258 (BioLegend Cat. No. 306015) AB_2264693 (BioLegend Cat. No. 306016)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, associates with CDw131, 70 kD
- Distribution
-
Myeloid precursors, basophils, mast cells, macrophages, dendritic cells, megakaryocytes, subset of lymphocytes
- Function
- Hematopoietic cell proliferation, differentiation
- Ligand/Receptor
- IL-3
- Cell Type
- Basophils, Dendritic cells, Hematopoietic stem and progenitors, Lymphocytes, Macrophages, Mast cells, Megakaryocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Miyajima A, et al. 1993. Blood 82:1960.
- Gene ID
- 3563 View all products for this Gene ID
- UniProt
- View information about CD123 on UniProt.org
