PE/Cyanine7 anti-human CD123 Antibody
- 产品名称：
- PE/Cyanine7 anti-human CD123 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 306009
- 产品应用：
- 306009
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human IL-3Rα transfected COS cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The CD123 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone 6H6 does not inhibit IL-3 binding to low- or high-affinity IL-3Rs. Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, and immunohistochemical staining of acetone-fixed frozen sections2?and also paraformaldehyde fixed paraffin embedded tissue7.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Sun Q, et al. 1996. Blood 87:83. (IP, WB)
- Herling M, et al. 2003. Blood 101:5007. (IHC)
- Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
- Martin-Gayo E, et al. 2010. Blood 115:5366. PubMed
- Chen SC, et al. 2010. Arch Dermatol Res. 302:113. PubMed
- Liu Y, et al. 2012. Food Chem Toxicol. 50:1920. PubMed
- Peduzzi E, et al. 2007. J. Invest. Dermatol. 127:638. (IHC)
- Product Citations
-
- Montes de Oca M, et al. 2016. Cell Rep. 17:399-412. PubMed
- Han L, et al. 2012. PLoS One. 4:e7989. PubMed
- Wieland S, et al. 2014. J Virol. 88:752.. PubMed
- Yamauchi T et al. 2018. Cancer cell. 33(3):386-400 . PubMed
- Hagan T, et al. 2020. Cell. 178(6):1313-1328.e13.. PubMed
- Royle C, et al. 2014. J Immunol. 193:3538. PubMed
- de Boer B et al. 2018. Cancer cell. 34(4):674-689 . PubMed
- Schwartz JA, et al. 2018. J Virol. 92:19. PubMed
- Kanakoudi-Tsakalidou F, et al. 2014. Lupus. 23:305. PubMed
- Greer A, et al. 2014. PLoS One. 9:99084. PubMed
- Iwabuchi R, et al. 2021. Frontiers in Immunology. 12:643040. PubMed
- Tillack K, et al. 2012. J Immunol. 188:3150. PubMed
- Hasan S, et al. 2017. Am J Physiol Cell Physiol. 312:C286. PubMed
- Woodberry T, et al. 2017. Infect Immun. 85:e00986. PubMed
- Baskar R, et al. 2022. Cell Rep Methods. 2:. PubMed
- Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
- Bradley T et al. 2018. Cell. 175(2):387-399 . PubMed
- Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
- Lu J, et al. 2021. Front Immunol. 12:732612. PubMed
- Bziat V, et al. 2021. Cell. . PubMed
- Nilsson JS, et al. 2019. Oncol Lett. 2.484027778. PubMed
- Webb K et al. 2018. Frontiers in immunology. 2.574305556 . PubMed
- Louka E, et al. 2021. Journal of Experimental Medicine. 218(2):. PubMed
- Chen YL, et al. 2020. J Exp Med. 217:. PubMed
- Rodriguez-Meira A, et al. 2020. STAR Protoc. 1:100125. PubMed
- Lv L, et al. 2019. Exp Ther Med. 17:1360. PubMed
- Qi Y, et al. 2012. PLoS One. 7:e39072. PubMed
- Suszczyk D, et al. 2022. Int J Mol Sci. 23:. PubMed
- Kivis?kk P, et al. 2014. PLoS One. 9:103716. PubMed
- Finotti G, et al. 2016. J Leukoc Biol. 99: 107 - 119. PubMed
- Rodrigues E, et al. 2020. Nat Commun. 3.99375. PubMed
- Lavaert M, et al. 2020. Frontiers in Immunology. 1.610416667. PubMed
- Ianniciello A, et al. 2021. Sci Transl Med. 13:eabd5016. PubMed
- Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
- Bill M, et al. 2018. J Cell Mol Med. 22:2311. PubMed
- Rodriguez‐Meira A et al. 2019. Molecular cell. 73(6):1292-1305 . PubMed
- RRID
- AB_493577 (BioLegend Cat. No. 306009) AB_493576 (BioLegend Cat. No. 306010)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, associates with CDw131, 70 kD
- Distribution
-
Myeloid precursors, basophils, mast cells, macrophages, dendritic cells, megakaryocytes, subset of lymphocytes
- Function
- Hematopoietic cell proliferation, differentiation
- Ligand/Receptor
- IL-3
- Cell Type
- Basophils, Dendritic cells, Hematopoietic stem and progenitors, Lymphocytes, Macrophages, Mast cells, Megakaryocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Miyajima A, et al. 1993. Blood 82:1960.
- Gene ID
- 3563 View all products for this Gene ID
- UniProt
- View information about CD123 on UniProt.org
