Purified anti-PRC1 Antibody
- 产品名称：
- Purified anti-PRC1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 629001
- 产品应用：
- 629001
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Amino Acid: 1-150
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
KO/KD-WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.5 - 5.0 ?g per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Udy D, et al. 2015. PLoS One. 10: 0134738. PubMed
- Elting MW et al. 2017. Current biology : CB. 27(14):2112-2122 . PubMed
- Suresh P, et al. 2020. eLife. 9:e53807.. PubMed
- RRID
- AB_2169532 (BioLegend Cat. No. 629001) AB_2169531 (BioLegend Cat. No. 629002)
- Structure
- Human PRC1 has 4 isoforms with MW ranging from 61-72 kD.
- Distribution
-
Cell cycle-dependent; nuclear, mitotic spindle, cell mid-body
- Function
- Mitotic spindle-associated CDK substrate protein required for cytokinesis, maintains the spindle midzone
- Interaction
- Cdc2, Cdk2
- Modification
- Phosphorylation
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication, Cell Motility/Cytoskeleton/Structure
- Antigen References
-
1. Jiang W, et al. 1998. Mol. Cell 2:877.
2. Mollinari C, et al. 2002. J. Cell Biol. 157:1175.
- Gene ID
- 9055 View all products for this Gene ID
- UniProt
- View information about PRC1 on UniProt.org
