Purified anti-TREM-2 Antibody
- 产品名称：
- Purified anti-TREM-2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 824803
- 产品应用：
- 824803
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse TREM-2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house?
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Koga?T, et al. 3004. Nature. 428:758. (FC, IP)
- RRID
- AB_2922646 (BioLegend Cat. No. 824803) AB_2922646 (BioLegend Cat. No. 824804)
- Structure
- 26 kD transmembrane glycoprotein, member of the immunoglobulin superfamily
- Distribution
-
Subset of macrophages, osteoclasts and microglia, immature dendritic cells
- Function
- Removal of apoptotic cells, organic matrix and macromolecules, bone modeling
- Interaction
- DNAX-activation protein 12 (DAP12)
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience
- Antigen References
-
- Leyns CEG, et al. 2019. Nat Neurosci. 22:1217-22.
- Zhong L, et al. 2019. Nat Commun.?10:1365.
- Parhizkar S, et al. 2019. Nat Neurosci. 22:191-204.
- Filipello F, et al. 2018. Immunity. 48:979-91.
- Gene ID
- 83433 View all products for this Gene ID
- UniProt
- View information about TREM-2 on UniProt.org
