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Purified anti-mouse CD19 Antibody
产品名称:
Purified anti-mouse CD19 Antibody
产品类别:
抗体
产品编号:
115501
产品应用:
115501
[价格]
规格 价格 库存
50µg ¥ 504 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD19-expressing K562 human erythroleukemia cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
CyTOF? - Verified
IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence7.

Application References

(PubMed link indicates BioLegend citation)
  1. Shoham T, et al. 2003. J. Immunol. 171:4062. (FC)
  2. Goodyear CS, et al. 2004. J. Immunol. 172:2870. (FC)
  3. Kamimura D, et al. 2006. J. Immunol. 177:306. (FC)
  4. Andoniou CE, et al. 2005. Nat. Immunol. 6:1011. (FC)
  5. Lawson BR, et al. 2007. J. Immunol. 178:5366. (FC)
  6. Phan TG, et al. 2007. Nat. Immunol. 8:992. (FC)
  7. Hayashida K, et al. 2008. J. Biol. Chem. 283:19895. (IF) PubMed
  8. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  9. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  10. Stadnisky MD, et al. 2011. Blood. 117:5133. (FC) PubMed
  11. Perlot T, et al. 2012. J. Immunol. 188:1201. (FC) PubMed
  12. Olive V, et al. 2013. Elife. 2:822. PubMed
  13. Miyai T, et al. 2014. PNAS. 111:11780. PubMed
Product Citations
  1. Tersteegen A, et al. 2021. Infect Immun. 89:. PubMed
  2. Hu J, et al. 2019. Am J Transl Res. 3.043055556. PubMed
  3. Fernandes V, et al. 2020. PLoS Pathog. 16:e1008464. PubMed
  4. Wan Mohd Zawawi WFA, et al. 2021. Sci Rep. 11:10278. PubMed
  5. Boal-Carvalho I, et al. 2020. EMBO Rep. 21:e50421. PubMed
  6. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  7. Mazor R, et al. 2018. Proc Natl Acad Sci U S A. 115:E733. PubMed
  8. Field CS, et al. 2018. Oncoimmunology. 7:e1376154. PubMed
  9. Carpenter SM, et al. 2017. PLoS Pathog. 13:e1006704. PubMed
  10. Thulasingam S, et al. 2019. Int J Mol Sci. 20. PubMed
  11. Joseph R, et al. 2021. Br J Cancer. 125:176. PubMed
  12. Schafflick D, et al. 2020. Nat Commun. 247:11. PubMed
  13. Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed
  14. Taylor NA, et al. 2017. J Clin Invest. 127:3472. PubMed
  15. Hilligan KL, et al. 2020. Nat Commun. 11:5637. PubMed
  16. Suzuki Y, et al. 2021. FEBS Open Bio. 11:2619. PubMed
  17. Yan J, et al. 2020. Cancer Immunol Res. 8:356. PubMed
  18. Chen L, et al. 2020. Front Immunol. 11:584458. PubMed
  19. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  20. He LD, et al. 2021. EMBO Rep. 22:e52196. PubMed
  21. Manni M, et al. 2018. Nat Immunol. 1.074305556. PubMed
  22. Ma W, et al. 2017. Sci Rep. . 10.1038/s41598-017-15661-6. PubMed
  23. Lim PJ, et al. 2019. Nat Metab. 0.402083333. PubMed
  24. McFarlane AJ, et al. 2017. J Allergy Clin Immunol. 140:1068. PubMed
  25. Borges TJ, et al. 2018. Nat Commun. 9:3482. PubMed
  26. Hoves S, et al. 2018. J Exp Med. 215:859. PubMed
  27. You X, et al. 2022. Front Genet. 12:790990. PubMed
  28. Godoy-Calderón MJ, et al. 2018. Oncotarget. 8:11370. PubMed
  29. Nascimento DC, et al. 2017. Nat Commun. 8:14919. PubMed
  30. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  31. Majer O, et al. 2019. Nature. 575:366. PubMed
  32. Chen HW, et al. 2021. Biomedicines. 9:. PubMed
  33. Zelazowska MA, et al. 2020. Life Sci Alliance. :3. PubMed
  34. Rozanski C, et al. 2015. J Immunol. 194:4717. PubMed
  35. Oyarce K, et al. 2018. Front Immunol. 9:112. PubMed
  36. Rigo MM, et al. 2020. FEBS J. :. PubMed
  37. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  38. Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed
  39. Seo SU, et al. 2021. Front Immunol. 12:697162. PubMed
  40. Goh W, et al. 2020. Cell Rep. 33:108285. PubMed
  41. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  42. Brownlie D, et al. 2021. J Immunother Cancer. 9:. PubMed
  43. Yang J, et al. 2019. Front Immunol. 2.492361111. PubMed
  44. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  45. Majri SS, et al. 2018. J Immunol. 200:110. PubMed
  46. Cui X, et al. 2017. J Immunol. 199:4066. PubMed
  47. Penninger T 2012. J Immunol. 188:1201. PubMed
  48. Korin B, et al. 2020. Sleep. :43. PubMed
  49. Zhu J et al. 2017. Cell stem cell. 20(3):374-384 . PubMed
  50. Hayashida K, et al. 2008. J Biol Chem. 283:19895. PubMed
  51. Stevens MY, et al. 2020. J Neuroinflammation. 0.899305556. PubMed
  52. Englezou PC, et al. 2018. Mol Ther Nucleic Acids. 12:118. PubMed
  53. Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed
  54. Atif SM, et al. 2019. JCI Insight. 4:e125494. PubMed
  55. Leist SR, et al. 2019. PLoS One. 14:e0220126. PubMed
  56. Khameneh HJ, et al. 2017. J Immunol. 198:196. PubMed
  57. Stadnisky M, et al. 2011. Blood. 117:5133. PubMed
  58. K?stele V, et al. 2021. Mucosal Immunol. 14:717. PubMed
  59. Hwang JY, et al. 2020. Front Immunol. 11:570661. PubMed
  60. Sutiwisesak R, et al. 2020. PLoS Pathog. 16:e1009000. PubMed
  61. Chen YQ, et al. 2019. J Immunother Cancer. 0.415277778. PubMed
RRID
AB_313636 (BioLegend Cat. No. 115501) AB_313637 (BioLegend Cat. No. 115502)

Antigen Details

Structure
Ig superfamily, associates with CD21 and CD81, 95 kD
Distribution

Pro-B cells to mature B cells (during development), follicular dendritic cells

Function
Modulates B cell activation and differentiation
Ligand/Receptor
CD21, CD81, Leu-13
Cell Type
B cells, Dendritic cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF, et al. 1994. Immunol. Today 15:437.

Gene ID
12478 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

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