Purified anti-FXR1 Antibody
- 产品名称：
- Purified anti-FXR1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 867001
- 产品应用：
- 867001
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human FXR1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
ICC - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2 - 10 ?g per ml.?For immunohistochemistry, a concentration range of 1 - 5 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- ??? Xu XL, et al. 2011. J. Neurosci. 31(39):13705-9. (WB)
- ??? Battle DJ, et al. 2007. J. Biol. Chem. 282(38):27953-9. (ICC)
- RRID
- AB_2810795 (BioLegend Cat. No. 867001) AB_2810796 (BioLegend Cat. No. 867002)
- Structure
- FXR1 is a 621 amino acid protein with predicted molecular mass of ~ 70 kD and observed molecular mass of ~ 75kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Cytosol and nucleus
- Function
- FXR1 is an RNA binding protein involved in neurodevelopmental diseases such as autism, schizophrenia, and fragile X mental retardation.
- Interaction
- Polyribosome, FXR2, FMR1, CYFIP2
- Cell Type
- Dopaminergic Neurons, GABAergic Neurons, Neurons, Oligodendrocytes
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Signal Transduction, Synaptic Biology, Transcription Factors
- Molecular Family
- Postsynaptic proteins, Presynaptic proteins
- Antigen References
-
- ??? Khlghatyan J, Beaulieu JM. 2018. Front Synaptic. Neurosci. 10:22.
- ??? Bardoni B, et al. 2001. Brain Res. Bull. 56:375-82.
- ??? Inoue SB, et al. 2000. J. Med. Invest. 47(3-4):101.
- Gene ID
- 8087 View all products for this Gene ID
- UniProt
- View information about FXR1 on UniProt.org
