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Purified anti-FMRP Antibody (Previously Covance ca
产品名称:
Purified anti-FMRP Antibody (Previously Covance ca
产品类别:
抗体
产品编号:
834602
产品应用:
834602
[价格]
规格 价格 库存
25µL ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a recombinant protein isolated from baculovirus.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 10 ?g per ml.?For immunocytochemistry, a concentration range of 5.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is effective in immunoblotting (WB) and immunocytochemistry (ICC).

The epitope for 6B8/FMRP lies between amino acids 345-350 of human FMRP. This clone does not cross react with FXR1 or FXR2 and is human specific.

This clone is also known as 6B8.

Application References

(PubMed link indicates BioLegend citation)
  1. LaFauci G, et al. 2013. J Mol Diagn. 15: 508-17
Product Citations
  1. Yildirim Z, et al. 2022. EMBO Mol Med. 14:e15344. PubMed
  2. Chakraborty A, et al. 2020. Cell Rep. 32:108179. PubMed
  3. Gustin SLF, et al. 2018. J Assist Reprod Genet. 35:1443. PubMed
  4. Aryal S, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  5. Xie N, et al. 2016. PLoS One. 11:e0165499. PubMed
RRID
AB_2750046 (BioLegend Cat. No. 834602) AB_2564992 (BioLegend Cat. No. 834601)

Antigen Details

Structure
Expected MW: 68-80 kD (smaller truncations of FMRP seen at lower molecular weights)
Biology Area
Cell Biology, Neuroscience, Synaptic Biology, Transcription Factors
Molecular Family
Postsynaptic proteins, Presynaptic proteins
Gene ID
2332 View all products for this Gene ID
UniProt
View information about FMRP on UniProt.org

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