Purified anti-FMRP Antibody (Previously Covance ca
- 产品名称:
- Purified anti-FMRP Antibody (Previously Covance ca
- 产品类别:
- 抗体
- 产品编号:
- 834602
- 产品应用:
- 834602
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a recombinant protein isolated from baculovirus.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
-
WB - Quality tested
ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 10 ?g per ml.?For immunocytochemistry, a concentration range of 5.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is effective in immunoblotting (WB) and immunocytochemistry (ICC).
The epitope for 6B8/FMRP lies between amino acids 345-350 of human FMRP. This clone does not cross react with FXR1 or FXR2 and is human specific.
This clone is also known as 6B8.
- Application References
(PubMed link indicates BioLegend citation) -
- LaFauci G, et al. 2013. J Mol Diagn. 15: 508-17
- Product Citations
-
- Yildirim Z, et al. 2022. EMBO Mol Med. 14:e15344. PubMed
- Chakraborty A, et al. 2020. Cell Rep. 32:108179. PubMed
- Gustin SLF, et al. 2018. J Assist Reprod Genet. 35:1443. PubMed
- Aryal S, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
- Xie N, et al. 2016. PLoS One. 11:e0165499. PubMed
- RRID
- AB_2750046 (BioLegend Cat. No. 834602) AB_2564992 (BioLegend Cat. No. 834601)