Purified anti-Bax Antibody
- 产品名称：
- Purified anti-Bax Antibody
- 产品类别：
- 抗体
- 产品编号：
- 633801
- 产品应用：
- 633801
- Verified Reactivity
- Human, Mouse, Rat, Monkey
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Amino acid:12-24 common to human, mouse, and rat Bax protein
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store undiluted at between 2°C and 8°C.
- Application
-
IP - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunoprecipitation. This antibody can be used at 2-4 ?g /1 x107 cell equivalents for immunoprecipitation. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Hsu YT, et al. 1997. J. Biol. Chem. 272:13829.
- Liu G, et al. 2013. J. Immunol. 191:2680. PubMed
- Product Citations
-
- Oda SK, et al. 2020. J Exp Med. 217: . PubMed
- Liu G, et al. 2013. J Immunol. 191:2680. PubMed
- RRID
- AB_2227699 (BioLegend Cat. No. 633801) AB_2061543 (BioLegend Cat. No. 633802)
- Structure
- Forms homodimers and heterodimers with Bcl-2, approximately 21 kD
- Distribution
- Cytoplasm, mitochondria, nucleus. Expressed in hematopoietic stem cells, ovary, lymph node
- Function
- Induces cell death through the process of apoptosis by acting on mitochondria.
- Interaction
- 14-3-3 theta, VDAC1, Bcl-2, solute carrier family 25, mitochondrial carrier member 4
- Cell Type
- Hematopoietic stem and progenitors
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Neuroscience
- Antigen References
-
1. LeBlanc H, et al. 2002. Nat. Med. 8:274.
2. Marzo I, et al. 1998. Science 281:2027.
3. Miyashita T et al. 1995. Cell 80:293.
4. Oltvai ZN, et al. 1993. Cell 74:609.
- Gene ID
- 581 View all products for this Gene ID
- UniProt
- View information about Bax on UniProt.org
