PE anti-human CD164 Antibody
- 产品名称：
- PE anti-human CD164 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 324808
- 产品应用：
- 324808
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3504 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- T-47D breast carcinoma line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting2,3 under non-reducing conditions (detects an 80-100 kD protein as well as a high molecular weight aggregate of approximately 220 kD), and immunofluorescence3.
- Application References
(PubMed link indicates BioLegend citation) -
- Watt SM, et al. 1998. Blood 92:849.
- Watt SM, et al. 2000. Blood 95:3113.
- Doyonnas R, et al. 2000. J. Immunol. 165:840.
- Vogel W, et al. 2002. Haematologica 88:126.
- Product Citations
-
- Goodnough LH, et al. 2020. JBMR Plus. 4:e10398. PubMed
- Ambrosi TH, et al. 2020. Aging Cell. 19:e13164. PubMed
- Pellin D, et al. 2019. Nat Commun. 10:2395. PubMed
- RRID
- AB_2072587 (BioLegend Cat. No. 324808)
- Structure
- Single pass transmembrane protein with short cytoplasmic tail. Highly N- and O-glycosylated, contains sialic acid and a Ser-Gly motif that may serve as an attachment for a glycosaminoglycan side chain. Three splice variants have been reported with apparen
- Distribution
-
Expressed in bone marrow, bone marrow stromal cells, and CD34+ hematopoietic cells myeloid and erythroid progenitors; activated basophils. Expressed on a variety of carcinomas and leukemic cells. Also expressed in the small intestine, colon, l
- Function
- Plays a role in cell adhesion and proliferation, negative signaling molecule for hematopoietic progenitor cells. Has also been reported to be involved in myogenic differentiation and cancer metastasis
- Cell Type
- Basophils, Hematopoietic stem and progenitors, Leukemia
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Zannettino ACW, et al. 1998. Blood 92:2613.
2. Havens AM, et al. 2006. BMC Cancer 6:195.
3. Lee YN, et al. 2001. Mol. Cell. Biol. 21:7696.
- Gene ID
- 8763 View all products for this Gene ID
- UniProt
- View information about CD164 on UniProt.org
