Alexa Fluor® 594 anti-human CD324 (E-Cadherin)-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 2472	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

T-47D cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

IHC-P - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.5 - 5.0 ?g/ml is suggested.?For immunocytochemistry, a concentration range of 2.5 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Application References (PubMed link indicates BioLegend citation)

Armeanu S, et al. 1995. J. Cell Biol. 131:243.
Bühring HJ, et al. 1996. Leukemia 10:106.
Yauch RL, et al. 2005. Clin. Cancer Res. 11:8686. (WB)
Oeztuerk-Winder F, et al. 2012. EMBO J. 31:3431. (FC) PubMed
Ardehali R, et al. 2013. PNAS. 110:3405. PubMed
Rasanen K, et al. 2013. Mol Cell Protecomics. 12:3778. PubMed
Chaudhury A, et al. 2014. Nucleic Acids Res. 42:86. PubMed
Milne P, et al. 2015. Blood. 125:470. PubMed

RRID

AB_2563211 (BioLegend Cat. No. 324118)

Antigen Details

Structure: Member of the cadherin superfamily. Calcium-dependent, transmembrane cell-cell adhesion glycoprotein composed of 4 extracellular cadherin repeats and a highly conserved cytoplasmic tail region. Predicted molecular weight approximately 100 kD.
Distribution: Widely expressed in epithelial cells in the colon, uterus, liver, keratinocytes, brain, heart, muscle, kidney, and pancreas, as well as erythroid cells
Function: Cell adhesion molecule involved in development, bacterial pathogenesis, and tumor invasion. The ectodomain of CD324 mediates bacterial adhesion to mammalian cell, while the cytoplasmic domain is required for internalization.
Interaction: Interacts with a variety of proteins including erbin, ezrin, caspase-3, caspase 8, EGF receptor, β-catenin, presenilin 1, casein kinase II, and others
Ligand/Receptor: α_Eβ₇ integrin
Modification: Phosphorylated on multiple residues (S857, S866, S870, S872), proteolytically cleaved at reside D769 by caspase-3.
Cell Type: Embryonic Stem Cells, Epithelial cells, Erythrocytes
Biology Area: Cell Biology, Immunology, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Overduin M, et al. 1995. Science 267:386.
2. Boggon TJ, et al. 2002. Science 296:1303.
3. Berx G, et al. 1995. EMBO J. 14:6107.
4. Perl AK, et al. 1998. Nature 392:190.
Gene ID: 999 View all products for this Gene ID
UniProt: View information about CD324 on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们