Biotin anti-mouse TSLP Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 2112	1

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Thymus stromal lymphopoietin
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application: ELISA Detection - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by ELISA assay. For ELISA detection applications, a concentration range of 0.5-2.0 ?g/ml is recommended. To obtain a linear standard curve, serial dilutions of TSLP recombinant protein ranging from 2000 to 31.3 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: The biotinylated 65B12 antibody is useful as a detection antibody in a sandwich ELISA, when used in conjunction with purified 28F12 antibody (Cat. No. 515202) as the capture antibody.
RRID: AB_2561715 (BioLegend Cat. No. 521903) AB_2561716 (BioLegend Cat. No. 521904)

Structure: Cytokine
Distribution: Epithelial cells, mast cells, basophils, epidermal keratinocytes in atopic dermatitis, synovial fibroblast in arthritis rheumatoid, human airway smooth muscle cells
Function: Induces proliferation of na??ve T cells, the release of T cell-attracting chemokines (CCL17 and CCL22) from monocytes, and the T cell stimulatory capacity of CD11c+ subset of dendritic cells; drives Th2 differentiation, drives Th2 cytokine-mediated inflammation to promote basophil hematopoiesis
Interaction: Monocyte, dendritic cells, activated human basophils, activated human T cells, Langerhans cells, B cells, mast cells, activated pulmonary Tregs, NKT cells
Ligand/Receptor: Heterodimeric receptor complex composed of the IL-7 receptor α chain (IL-7Rα) and the TSLP receptor (TSLPR or CRLF2)
Cell Type: Basophils, Epithelial cells, Fibroblasts, Mast cells
Biology Area: Immunology
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Levin SD,?et al.?1999.?J. Immunol.?162:677.?
2. Reche PA,?et al.?2001.?J. Immunol.?167:336.?
3. Omori M and Steven Ziegler. 2007.?J. Immunol.?178:1396.?
4. Rochman I,?et al.?2007.?J. Immunol.?178:6720.?
5. Mazzucchelli R,?et al.?2008.?Blood?112:3283.?
6. Siracusa MC,?et al.?2011.?Nature?477:229.?
7. Nguyen KD,?et al.?2010.?Allergy Asthma Clin. Immunol.?6:4.
Gene ID: 53603 View all products for this Gene ID
UniProt: View information about TSLP on UniProt.org