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Purified anti-human CCR10 Antibody
产品名称:
Purified anti-human CCR10 Antibody
产品类别:
抗体
产品编号:
341502
产品应用:
341502
[价格]
规格 价格 库存
100µg ¥ 2748 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
N-terminal peptide of human CCR10
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

It has been observed that clone 6588-5?can interact with some tandem-dye antibody conjugates during multi-color staining, potentially leading to unwanted staining. These dyes include PE/Cy7, PE/Cy5, PE/Dazzle? 594, APC/Cy7, APC/Fire? 750, and PerCP/Cy5.5.? This interaction can be resolved by sequentially staining with the 6588-5 antibody first and then followed by other antibodies of interest.

Product Citations
  1. Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
RRID
AB_1595419 (BioLegend Cat. No. 341502)

Antigen Details

Structure
G-protein-coupled seven transmembrane protein
Distribution

Small subsets of T memory cells and IgA-secreting cells, EBV-immortalized B cells, dermal microvascular endothelial cells and dermal fibroblasts

Function
T cell homing into cutaneous site, regulation of IgA-secreting cells migration
Ligand/Receptor
CCL27 (CTACK/ALP/ILC/ESkine), CCL28 (MEC)
Cell Type
B cells, Endothelial cells, Fibroblasts, T cells
Biology Area
Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Hudak S, et al. 2002. J. Immunol. 169:1189
2. Kunkel EJ, et al. 2003. J. Clin. Invest. 111:1001
3. Homey B, et al. 2002. Nature Medicine. 8:157
4. Nakayama T, et al. 2002. J. Virol. 76:3072

Gene ID
2826 View all products for this Gene ID
UniProt
View information about CCR10 on UniProt.org

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