PE anti-human CCR10 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1836	1

Product Details

Verified Reactivity

Human

Reported Reactivity

African Green, Baboon, Cynomolgus, Rhesus

Antibody Type

Monoclonal

Host Species

Armenian Hamster

Immunogen

N-terminal peptide of human CCR10

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

It has been observed that clone 6588-5?can interact with some tandem-dye antibody conjugates during multi-color staining, potentially leading to unwanted staining. These dyes include PE/Cy7, PE/Cy5, PE/Dazzle? 594, APC/Cy7, APC/Fire? 750, and PerCP/Cy5.5.? This interaction can be resolved by sequentially staining with the 6588-5 antibody first and then followed by other antibodies of interest.

Product Citations

Hohmann MS, et al. 2021. JCI Insight. 6:. PubMed
Sugita S, et al. 2013. Invest Ophthalmol Vis Sci . 54:6926. PubMed
Qualai J, et al. 2016. PLoS One. 11: 0156605. PubMed
Magri G et al. 2017. Immunity. 47(1):118-134 . PubMed
Kubin ME, et al. 2017. Acta Derm Venereol. 97:449. PubMed
Yin S, et al. 2015. Sci Rep. 5: 14432. PubMed
Zamarin D, et al. 2020. Clin Cancer Res. 26:4531. PubMed

RRID

AB_1595542 (BioLegend Cat. No. 341503) AB_1595446 (BioLegend Cat. No. 341504)

Antigen Details

Structure: G-protein-coupled seven transmembrane protein
Distribution: Small subsets of T memory cells and IgA-secreting cells, EBV-immortalized B cells, dermal microvascular endothelial cells and dermal fibroblasts
Function: T cell homing into cutaneous site, regulation of IgA-secreting cells migration
Ligand/Receptor: CCL27 (CTACK/ALP/ILC/ESkine), CCL28 (MEC)
Cell Type: B cells, Endothelial cells, Fibroblasts, T cells
Biology Area: Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Hudak S, et al. 2002. J. Immunol. 169:1189
2. Kunkel EJ, et al. 2003. J. Clin. Invest. 111:1001
3. Homey B, et al. 2002. Nature Medicine. 8:157
4. Nakayama T, et al. 2002. J. Virol. 76:3072
Gene ID: 2826 View all products for this Gene ID
UniProt: View information about CCR10 on UniProt.org

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