PE anti-human CD357 (GITR) Antibody
- 产品名称：
- PE anti-human CD357 (GITR) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 311604
- 产品应用：
- 311604
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 3648 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
The LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 311606).
- Application References
(PubMed link indicates BioLegend citation) -
- Kwon B, et al. 1999. J. Biol. Chem. 274:6056.
- Zhou Z, et al. 2008. Proc Natl Acad Sci USA . 105:5465 PubMed
- Product Citations
-
- Ferguson ID, et al. 2022. Nat Commun. 13:4121. PubMed
- Lacal P, et al. 2013. J Pharmacol Exp Ther. 347:164. PubMed
- Zeng Y et al. 2019. Immunity. 51(5):930-948 . PubMed
- RRID
- AB_314886 (BioLegend Cat. No. 311603) AB_314887 (BioLegend Cat. No. 311604)
- Structure
- TNFR superfamily, 234-amino acid type I transmembrane protein, 25 kD
- Distribution
-
Activated lymphocytes
- Function
- Interacts with TRAF's 1-3, but not TRAF 5 or 6, mediates NF-κB activation through the TRAF2/NIK pathway
- Ligand/Receptor
- GITRL
- Cell Type
- Lymphocytes, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kwon B, et al. 1999. J. Biol. Chem. 274:6056.
- Gene ID
- 8784 View all products for this Gene ID
- UniProt
- View information about CD357 on UniProt.org
