Purified anti-Lamin B1 Antibody
- 产品名称：
- Purified anti-Lamin B1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 869801
- 产品应用：
- 869801
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Lamin B1 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 ?g/mL.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 10 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2820180 (BioLegend Cat. No. 869801) AB_2820181 (BioLegend Cat. No. 869802)
- Structure
- Human lamin B1 is a 586 amino acid protein with a predicted molecular mass of 66 kD.
- Distribution
-
Tissue distribution: Ubiquitously expressed
Cellular distribution: Nucleus
- Function
- Lamin B1 is a component of the nuclear lamina, providing a framework for nuclear envelope.
- Interaction
- Lamin B1 interacts with lamin-associated peptides IA, IB, 2, and SPAG4 and SEPT12.
- Cell Type
- Astrocytes, Microglia, Neurons, Oligodendrocytes
- Biology Area
- Cell Biology, Cell Structure, Chromatin Remodeling/Epigenetics, Neurodegeneration, Neuroinflammation, Neuroscience
- Molecular Family
- Nuclear Markers
- Antigen References
-
- Padiath QS. et al. 2006. Nat Genet. 38(10):1114-23.
- Camps J. et al. 2015. Nucleus. 6(1):8-14.
- Mahajani S. et al. 2017. Sci Rep. 7(1):4897.
- Gene ID
- 4001 View all products for this Gene ID
- UniProt
- View information about Lamin B1 on UniProt.org
