PE/Cyanine7 anti-human Siglec-10 Antibody
- 产品名称：
- PE/Cyanine7 anti-human Siglec-10 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 347608
- 产品应用：
- 347608
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 4932 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Siglec-10 fused to human IgG Fc
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Munday J, et al. 2001. Biochem. J. 355:489
- Yokoi H, et al. 2006. Allergy. 61:769
- Kivi E, et al. 2009. Blood 114:5385
- Barkal AA, et al. 2019. Nature. 572(7769):392-396. (Agonist)
- RRID
- AB_2814275 (BioLegend Cat. No. 347607) AB_2814276 (BioLegend Cat. No. 347608)
- Structure
- Lectin, belongs to the Ig-superfamily, has one V-set Ig-like domain and three C2-set domains, a single transmembrane domain and one immunoreceptor tyrosine-based inhibitor motif (ITIM) in the cytoplasmic domain
- Distribution
-
Monocytes, eosinophils, B cells, and a subset of NK cells
- Function
- Cell adhesion, signal transduction
- Interaction
- SHP-1, PTPN6
- Ligand/Receptor
- CD24, vascular adhesion protein-1 (VAP-1)
- Bioactivity
- Inhibition of signal transduction by recruiting cytoplasmic phosphatases
- Cell Type
- B cells, Eosinophils, Monocytes, NK cells
- Biology Area
- Immunology
- Molecular Family
- Siglec Molecules
- Antigen References
-
1. Chen GY, et al. 2009. Science 323:1722
2. Aizawa H, et al. 2003. Genomics.82:521
3. Kitzig F, et al. 2002. Biochem Biophys Res Commun. 296:355
- Gene ID
- 89790 View all products for this Gene ID
- UniProt
- View information about Siglec-10 on UniProt.org
