Purified anti-GRB2 Antibody
- 产品名称：
- Purified anti-GRB2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 867101
- 产品应用：
- 867101
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human GRB2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2 ?g per ml. For formalin-fixed paraffin-embedded immunohistochemical staining, a concentration range of 2 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2810797 (BioLegend Cat. No. 867101) AB_2810798 (BioLegend Cat. No. 867102)
- Structure
- GRB2 is a 217 amino acid protein with predicted and observed molecular mass of ~25 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Plasma membrane, nucleus, cytosol, endosome, and Golgi apparatus
- Function
- GRB2 is an adapter protein that binds to activated SH2-containing proteins and plays an important role in determining cell fate.
- Interaction
- EGF receptors, PDGF receptors, and other proteins containing SH2 or SH3 domains.
- Cell Type
- Microglia, Neurons
- Biology Area
- Cancer Biomarkers, Cell Death, Neurodegeneration, Neuroscience, Signal Transduction
- Molecular Family
- Adaptor Proteins
- Antigen References
-
- Ijaz M, et al. 2018. Protein Pept Lett. 24(12):1084
- Paff M, et al. 2014. Hum Vaccin Immunother. 10(11):3322
- Belov AA and Mohammadi M. 2012. Sci Signal. 5(249):pe49
- Gene ID
- 2885 View all products for this Gene ID 14784 View all products for this Gene ID 81504 View all products for this Gene ID
- UniProt
- View information about GRB2 on UniProt.org
